Cancer immunology, or “immuno-oncology,” is a growing field of research that aims to discover innovative cancer immunotherapies to treat and impede the progression of the disease. Understanding how cancer evades the immune system is the basis of immuno-oncology.

With Indivumed’s scientific support you can, for example, identify the different types of immune cells and their state of activation, as well as the role of the tumor microenvironment.

Indivumed supports your immune oncology efforts with banked and prospective biospecimen from patients having received immune oncology treatment in combination with outstanding lab services.

This well-described biospecimen can be used in different read-outs like multiplex fluorescent IHC, proteomics, genomics, or cell biology methods.

Of course, the assays can be performed on tissue/fluids provided by the customer. In-house pathologists create read-outs using state-of-the-art digital histopathology to provide robust results for our customers’ research.

Resources

Product Profile Services

Dissociated Tumor Cells / Tumor Infiltrating Lymphocytes

Indivumed Services provides the prospective collection of fresh blood and tumor tissue for the preparation of dissociated tumor cells and isolation of TILs. Following that, immune cell subpopulations can be characterized by flow cytometry in-house.
Application Note

Flow Cytometry

To characterize immune cell phenotypes, Flow Cytometry is the key technology to use. In this note, we analyzed tumor infiltrating immune cells (TILs) using Indivumed Service’s tumor and adjacent normal tissue from CRC and NSCLC patients.
Product Profile Services

Immunohistochemistry Services/Digital Pathology

Our chromogenic and fluorescence multiplex IHC (fmIHC) service offers the possibility to analyze biomarkers and molecules of interested on tissue sections with the highest specificity.
Application Note

Immunohistochemistry Detection of Phospho-HER-3

Learn how we detected phospho-HER-3 in human breast cancer using immunohistochemistry. After evaluating the target specificity, we created a protocol with different approaches for this purpose.
Product Profile Services

Mutation Profiling

Indivumed Services performs highly standardized mutation profiling with different panels that detect somatic mutations in cancer-related genes by multiplexed targeted resequencing on the MiSeqDx platform (Illumina).
Product Profile

Overview – Indivumed Services Biobank

To support your research and development in personalized medicine, Indivumed Services offers Multi-omics Grade and Standard Grade Biospecimens with a high-quality guarantee and low usability failure rate.
Product Profile Services

Spatial Transcriptomics

As "Certified Service provider" of 10x Genomics, we offer the full workflow for your Spatial Transcriptomics project. Overcome the lack of morphological information within bulk RNA analysis and examine the total transcriptome in the morphological context with just one tissue section.
Product Profile Service

Single Cell Gene Expression Analysis Service

Single cell sequencing provides you with a deep insight into gene expression and opens the opportunity to characterize heterogeneous cell populations. We use the 10x Genomics technology, "Chromium Single Cell Gene Expression," for which we are a certified service provider.